Examining the Challenges of Indian Deep-Tech Startups: Pathway for Sustainable Entrepreneurial Practices

Authors

  • Shalini Katare
  • Vimala Raja Priya Mudapaka Indian Institute of Technology Hyderabad
  • Jayshree Patnaik Indian Institute of Technology Hyderabad https://orcid.org/0000-0002-4405-5308

Keywords:

Deep-Tech Startup, Valley of Death, TOE Framework, Commercialization, emerging markets

Abstract

Deep-tech startups are rooted in scientific and engineering innovations and hold transformative potential for addressing critical societal challenges in healthcare, clean energy, water treatment, and sustainable infrastructure. Unlike traditional digital startups, which scale swiftly via continuous innovation, deep-tech startups confront distinctive hurdles due to lengthy R&D periods, intensive capital investments, stringent regulatory compliance, and unpredictable market penetration. These conditions expose them to the Valley of Death (VoD), a critical phase in which promising innovations fail to reach commercial viability before funding is exhausted. This vulnerability stems from a fundamental misalignment between experimental outcomes and commercial viability, further compounded by systemic gaps in institutional support, including inadequate legal frameworks and limited market awareness in emerging market contexts. Despite growing scholarly interest in both the Valley of Death and the Technology–Organization–Environment (TOE) framework, there is limited research to explain how technological, organizational, and environmental conditions collectively produce specific commercialization barriers for deep-tech startups. This study addresses this gap through qualitative research with five deep-tech startups in India operating across agritech, healthcare technology, neurotechnology, nanotechnology, and cybersecurity. Thematic analysis of semi-structured interviews resulted in interrelated themes, each representing a different aspect of the TOE framework. The results reveal that technological, organizational, and environmental barriers are not isolated phenomena but dynamically reinforce one another, giving rise to three interrelated Valley of Death barriers: funding gaps, market translation failure, and legitimacy deficits. The proposed TOE–VoD framework therefore suggests that overcoming commercialization challenges in deep-tech startups requires an integrated perspective that simultaneously addresses technological, organizational, and environmental dimensions. The framework further provides founders with a diagnostic tool, policymakers with a rationale for multi-dimensional interventions, and researchers with a foundation for comparative and longitudinal inquiry into deep-tech commercialization across emerging market contexts.

Author Biographies

Shalini Katare

Shalini is currently a research intern at the Indian Institute of Technology Hyderabad. She has completed Master's degree in biological sciences (Zoology) from Jiwaji University, Gwalior, Madhya Pradesh, India

Vimala Raja Priya Mudapaka, Indian Institute of Technology Hyderabad

Vimala is currently pursuing her PhD from the Department of Entrepreneurship and Management at IIT Hyderabad. Her research interest centers around entrepreneurship, startups, and strategic management.

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Published

2026-09-11