Generative Artificial Intelligence for Recognition of Surgical Site Complications: the PRISCA Project

Authors

  • Isabel Carozzo On AIR srl
  • Elisa Bruzzo Nextage srl
  • Matteo Parodi FlairBit srl
  • Luca Giulio Brayda Nextage srl
  • Michele Minuto University of Genoa
  • Ennio Ottaviani On AIR srl

DOI:

https://doi.org/10.34190/icair.5.1.4346

Keywords:

Generative AI, Medical Image Classification, Telemedicine, Surgical Wounds

Abstract

The project PRISCA develops digital tools for postoperative monitoring and early detection of wound complications
(e.g., infections) through telemedicine solutions. The approach addresses concrete clinical needs, including the follow-up of
patients discharged from centers of surgical excellence located far from home, the optimization of hospital access, and the
early identification of at-risk situations. The output of the project will be a telemonitoring platform (mobile and web apps),
artificial intelligence modules for wound image analysis, and informative content for patients. The technological architecture
is designed to support timely intervention in case of wound-related complications, while also reducing unnecessary in-person
visits. The project’s main innovation is the use of an Artificial Intelligence module. It aims to enable healthcare professionals
to perform automated analysis of wound images for early detection of post-surgical complications. The limited availability
of public data was tackled by applying a data augmentation method and by integrating a generative AI model. It creates new
synthetic images based on real images and textual prompts. All generated images had been validated by clinicians and then
included in the final dataset. This approach ensures the model learns from a diverse set of images, increasing its robustness
and accuracy. The adopted detection model is YOLOv11, which localizes the wound and performs a pathological/nonpathological
classification. Results show good localization and promising classification accuracy. We performed a comparison
between the model trained on the original dataset and the version enhanced with synthetic data, in order to assess relative
improvements. These comparisons will help refine the model for better performance in real-world scenarios. The first results
show an increase in the performance of the model with augmented data but more systematic comparisons are needed.
Additional real images from a proprietary dataset currently being collected will also be integrated, further enhancing the AI's
ability to identify early complications.

Author Biographies

Elisa Bruzzo, Nextage srl

Elisa Bruzzo (female) is part of the Nextage’s staff working on Innovation Research projects.
Her main research areas are related to Health Informatics, with focus on Telemedicine,
Teletraining platforms and systems processing Electronic Health Records. During her
master’s degree (2018) she studied and published on image processing for lung ultrasound.

Matteo Parodi, FlairBit srl

Graduated with honors in Computer Engineering, Matteo Parodi (male) is one of the three co-founder of  FlairBit, a company that provides digital solutions based on data analytics,  algorithms, and artificial intelligence. In FlairBit, Matteo Parodi has the role of Project Manager and  Team Leader.

Luca Giulio Brayda, Nextage srl

Luca Brayda, PhD (male) is Nextage’s Area Manager, with a PhD thesis on
multi-microphone signal processing and 20+ of research in machine learning, human-robot
interfaces and cognitive sciences. He developed several hardware-software assistive
technologies for people with disabilities and is author of 50+ international publications and 4
international patents.

Michele Minuto, University of Genoa

Michele Minuto, MD, PhD, is an Associate Professor of General Surgery at the University of Genoa, European board certified in Endocrine Surgery. His clinical and research expertise focuses on thyroid, parathyroid, and adrenal surgery. He has performed over 4,000 procedures and authored more than 100 international publications in endocrine surgery.

Ennio Ottaviani, On AIR srl

Ennio Ottaviani, (male) is OnAIR’s CEO with a theoretical physics background and  40+ years of applied research in computer vision, optimization, machine learning and artificial intelligence. He developed several smart computer-based systems for industry and services automation and is author of 50+ international publications about AI applications.    

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Published

2025-12-04